Who Tobi Is For
People over 6 years old with cystic fibrosis who have P. aeruginosa in their lungs.
Who Shouldn’t Take Tobi
People who are allergic to tobramycin or other antibiotics in the same family (aminoglycosides).
How to Take It
Tobi is inhaled into the lungs using a machine called a nebulizer. It is usually taken every 12 hours. To prevent developing resistance, Tobi should be taken in cycles of 28 days on the medication followed by 28 days off.
Storage
Tobi should be stored in the refrigerator whenever possible. If refrigeration is not available, Tobi can be stored in a dark place at room temperature up to 77 degrees. Tobi should never be exposed to extreme heat or intense light. If the solution contains particles or appears cloudy, it should be discarded.
Side Effects
Some common side effects of Tobi include:
Sore throatHeadacheUnpleasant taste in the mouthHoarseness or change in voice
Safety Warnings
Some people who take Tobi have reported hearing loss, which may be permanent if it occurs. Tell your healthcare provider immediately if you have:
DizzinessRinging in the earsReduced hearing
Tobi can also cause bronchospasm, a condition that restricts the ability to breathe. Tell your healthcare provider immediately if you have:
Increased coughingWheezingShortness of breath
Before taking Tobi, tell your healthcare provider if you:
Are allergic to Tobi or other aminoglycoside antibitotics such as streptomycin, amikacin, kanamycin, neomycin, or gentamicinAre pregnant, or planning to become pregnantAre breastfeedingHave kidney or liver disease
Financial Assistance
A 28-day supply of Tobi is expensive, but it is covered by most insurance plans. If you do not have insurance or your insurance does not cover Tobi, Novartis has an assistance program that may be able to help if you meet the criteria.
